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Who Gets Sick in Space? Orbital Tourists May Offer Better Clues.

Doctors have poked and prodded NASA astronauts for years, and the astronauts, as government employees, have largely acceded to their roles as …

Who Gets Sick in Space? Orbital Tourists May Offer Better Clues.

Doctors have poked and prodded NASA astronauts for years, and the astronauts, as government employees, have largely acceded to their roles as test animals in studying how an alien environment — outer space — affects the human body.

But professional astronauts have historically been a small slice of humanity. Initially, they were chosen from the ranks of military test pilots who were white, physically fit men. Later, as NASA broadened its criteria, it still chose only astronauts who passed their physical thresholds.

But that could be changing as private spaceflight opens space to a more diverse cross section of humanity.

For scientists, the change will create a bonanza of new data on how the human body adapts to space.

The Inspiration4 mission, which launched on Wednesday, shows how medical researchers can benefit from the new commercial space travel. The crew of four, none of whom is a professional astronaut, will spend a fair amount of time in orbit helping to advance medical research.

One of the passengers, Hayley Arceneaux, exemplifies those possibilities. At 29, she is younger than most space travelers, a cancer survivor and will be the first person in space with a prosthesis — metal rods that were implanted after a tumor was removed from her left leg.

“We’re going to learn some things that are very fundamental,” said Dorit Donoviel, executive director of the Translational Research Institute for Space Health, or TRISH, at the Baylor College of Medicine in Houston, which is coordinating research during the Inspiration4 flight.

Research to date has revealed that fluids shift upward in the body in the absence of gravity — swollen heads, shrunken legs. The lack of gravity also weakens bones. Not only does radiation in space slam into DNA creating mutations, but the unusual conditions of weightlessness cause some genes to turn on and others to turn off. The biological repercussions of these alterations are not yet understood.

The crew aboard Inspiration4 will take 10 tests originally designed to gauge the mental performance of NASA astronauts each day. The tests take about 20 minutes to complete.

“It needed to be brief, because astronauts kind of hate doing these things,” said Dr. Mathias Basner, a professor of psychiatry at the University of Pennsylvania who is the lead investigator for that experiment.

But in a dangerous environment like space, small errors can lead to catastrophe.

“So we need our astronauts to perform at their best all the time,” Dr. Basner said. “Now, the problem is that humans are particularly bad at self-assessing their performance capability, especially in chronic exposure situations. If you sit in the same environment all the time, you think you’ll be fine, but you’re actually not.”

Wednesday’s launch from Cape Canaveral in Florida. The crew will perform several tests, from those designed to gauge mental performance and visual acuity, to trying out ultrasound devices that track how water shifts in their bodies in low gravity.Credit…Chandan Khanna/Agence France-Presse — Getty Images

One test is simply a square that appears on a screen, and one has to tap on it. The square changes position and progressively becomes smaller. That measures the reaction speed and eye-hand coordination.

Another measures what is known as psychomotor vigilance. First, the subject stares at a box on the screen. A stopwatch suddenly pops up within the box, counting the milliseconds until the subject presses a button. “Which is extremely sensitive to sleep deprivation,” Dr. Basner said.

Yet another test gauges a person’s ability to identify emotions in other people.

The test displays 20 faces showing a variety of emotions — happy, sad, angry, fearful or expressing no emotion. In a so-called bed rest study — lying down for extended periods of time mimics many of the physical effects of weightlessness in space — subjects were able to still correctly identify most of the emotions. But they took longer to identify them, and their responses skewed to more negative expressions.

Mark J. Shelhamer, a professor at Johns Hopkins Medicine, is gathering data on how spaceflight affects the vestibular system — the parts of the human body, particularly the inner ear, that maintain balance.

His research consists of two parts, to be conducted before launch and after the return to Earth. One will measure the crew members’ postures. “It’s just what it sounds like,” Dr. Shelhamer said. “It’s the ability to stand up. And the ability to stand up is not only based on muscle strength, but it’s based on coordination.”

The Inspiration4 crew members will hold a Windows tablet to their chests, put their feet together and close their eyes. Accelerators in the tablet will measure how much they sway as they stand.

“That’s not so hard to do on Earth,” Dr. Shelhamer said. “But it can be challenging after having spent some time in space.”

Dr. Shelhamer has also devised a test using the tablet to study whether weightlessness causes eyes to become misaligned. That could give hints of how the brain might become confused, disrupting the sense of balance.

What researchers want to learn is how to predict who becomes sick in space. Surprisingly, there is no correlation between who experiences motion sickness on Earth — on a boat rocking back and forth, during a long car trip, even short episodes of floating during parabolic plane flights — and those who become sick in orbit.

From left, Christopher Sembroski, Sian Proctor, Jared Isaacman and Ms. Arceneaux in the crew capsule, two minutes before launch.Credit…SpaceX, via Agence France-Presse — Getty Images

“We don’t understand this at all,” Dr. Shelhamer said. “It’s an embarrassment, because we would like to think that it’s the same fundamental mechanisms — the fact that the different sensory systems don’t match up.”

TRISH, the organization Dr. Donoviel leads, has built a database to store the study results that not only protects the privacy of private space travelers in accordance with the requirements of HIPAA, the Health Insurance Portability and Accountability Act, but will also allow researchers to compare data from different studies for one individual.

For instance, Dr. Shelhamer might want to know whether an individual whose ability to stand straight without swaying declined after a trip to space also encountered cognitive slowdowns while taking Dr. Basner’s tests in space. That is often not possible with how NASA reports data collected on its astronauts, he said.

In addition, the Inspiration4 crew members are wearing Apple Watches that will measure their heart beats and oxygen levels. They will also test out ultrasound devices that can track how water in their bodies shifts upward while they float in orbit. That could help solve the puzzle of the squashing of eyeballs and resulting shift in vision experienced by some astronauts.

The research does depend on how well the Inspiration4 crew feels during their trip. Because there is no way to predict who gets sick in space, it is possible that they all will and then they may not be able to do much research during the three-day trip.

“My worry is that they’re not going to enjoy their time in space,” Dr. Donoviel said. “They may not be able to carry out the experiments that we are sending up. So that is a risk that I’m taking.”

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100 mg fiyatcialis 5 mg fiyatviagra 100 mg fiyatcialis 5 mg fiyatcialis fiyat eczanepostegropostegrocinsel hastalıklarereksiyon sorunuacarkent escortbahariye escortcialis 20 mgcialis 100 mgcialis 5 mgcialis fiyatcialiscialis fiyatlarıviagra fiyatviagra siparişcialis satışcialis siparişviagra fiyatlarıkartal escortbedava bonus veren bahis siteleribahisgaziantep escortviagraviagra fiyatpostegropostegropostegroDubai escortsDubai escortsLondon escortsfree instagram followersMarmaris Escortpendik escortkartal escortkurtkoy escorttuzla escorthalkalı escortbayrampaşa escortbaşakşehir escortbahçelievler escortbağcılar escortbahçeşehir escortkadın giyimfantezi babydollfantezi çorapfantezi giyimKadın üst giyimkadın alt giyimkadın ayakkabıkadın atletbluz bodybot bootiekadın ceketkadın çizmekadın elbiseelbise abiyekadın eşofman altıkadın eşofman takımıAnkara escort bayanturgutreis escortpostegroweb postegroweb postegropostegroizmit escortistanbul escortkaynarca escortviagra 100 mg fiyatviagra 100 mg fiyatgaziantep escort bayanGüvenilir bahis SiteleriBalgat escortÇankaya escortCebeci escortDemetevler escortDikmen escortEryaman escortEsat escortEtlik escortKeçiören escortKızılay escortKolej escortRus escortSincan escortYenimahalle escortAtaşehir escortanadolu yakası escortAnadolu yakası escortAtaşehir escortAtaşehir escortKadıköy escortKadıköy escortÜmraniye escortÜmraniye escortBostancı escortBostancı escortbostancı escortpostegroadana escortadana escort bayanafyon escortacarkent escortacibadem escortadalar escortafyon escortalanya escort bayanalanya escortantalya escort bayanantalya escortartvin escortartvin escortbeylikdüzü escortbeylikdüzü escortbeylikdüzü escortbeylikdüzü escortbodrum escortbolu escortbolu escortburdur escortbursa escortbursa escortçanakkale escortçanakkale escortçeşme escortdidim escortdiyarbakır escortdiyarbakır escortedirne escortedirne escortelazığ escortelazığ escorterzincan escorterzincan escorterzurum escorterzurum escortbodrum escortbursa escortbursa escorteskişehir escorteskişehir escortgaziantep escortgaziantep escortgaziantep escortgiresun escortgiresun escortgümüşhane escorthatay escorthatay escortısparta escortısparta escortkars escortkastamonu escortkastamonu escortkayseri escortkayseri escortkıbrıs escortkıbrıs escortkonya escortkonya escortkuşadası escortkütahya escortkütahya escortmalatya escortmalatya escortmanisa escortmanisa escortmardin escortmardin escortmarmaris escortmersin escortnevşehir escortnevşehir escortniğde escortniğde escortordu escortordu escortrize escortrize escortsakarya escortsakarya escortsamsun escortsamsun escortşanlıurfa escortşanlıurfa escortsinop escortsinop escortsivas escortsivas escorttekirdağ escorttekirdağ escorttrabzon escorttrabzon escortuşak escortvan escortvan escortyalova escortyalova escortyozgat escortyozgat escortzonguldak escortzonguldak escortCoinbar girişSafirbet girişcratosslot girişAsyabahis girişTempobet girişMarsbahis girişBetebet girişVdcasino girişVevobahis girişBetper girişimajbet girişHoliganbet girişJojobet girişAnadolucasino girişArtemisbet girişbelugabahis girişbetvole girişinterbahis girişmilanobet girişZeytinburnu EscortYeşilköy EscortYenibosna EscortÜmraniye EscortTopkapı EscortTaksim EscortSuadiye EscortSınırsız EscortŞişman EscortŞişli EscortŞirinevler EscortSilivri EscortPendik EscortOrtaköy EscortOlgun EscortNişantaşı EscortMerter EscortMecidiyeköy EscortMaslak EscortMaltepe EscortMahmutbey EscortLevent EscortKurtköy EscortKüçükyalı EscortKüçükçekmece EscortKartal EscortKağıthane EscortKadıköy Escortİstanbul Escortİkitelli EscortHaramidere EscortHalkalı EscortGöztepe EscortGenç EscortFlorya EscortFındıkzade EscortFatih EscortEtiler EscortEsenyurt EscortEscort NumaralarıEscort BayanlarErenköy EscortElit Escortçekmeköy escortÇıtır Escortşerifali escortCihangir Escortümraniye escortüsküdar escortCevizli EscortCennet Mahallesi Escortsuadiye escortÇapa Escortkadıköy escortÇağlayan Escortgöztepe escortBüyükçekmece Escortbostancı escortgöztepe escortBostancı EscortBeyoğlu Escortsuadiye escorterenköy escortbostancı escortanadolu yakası escortavrupa yakası escortBeylikdüzü EscortBeşiktaş Escortanadolu yakası escortBayrampaşa EscortBaşakşehir Escortümraniye escortBakırköy Escortkadıköy escortBahçelievler Escortbostancı escortBağdat Caddesi Escortataşehir escortBağcılar Escortcevizli escortatalar escortmaltepe escortAvrupa Yakası Escortkartal escortmaltepe escortAvcılar EscortAtaşehir Escortümraniye escortsupertotobetrestbet girisbetpas girisbetbabayurtdisiaugenoperationbotox bruisinghepsibahisrexbetsuperbetinbetsatbets10romabettarafbetbetparkhilbetonbahisbahsegelbahigowinxbetelitbahisdinamobetbetmatiktimebetgebze escortleopard honeyAnkara escortUlus escortTunalı escortTandoğan escortSıhhiye escortRus escortMamak escortMamak escortGölbaşı escortCinsel sağlık ürünleriCinsel performans ilaçlarıCialis fiyatCialis 20 mg fiyatCialis 100 mg fiyatCialis 30 lu tablet fiyatViagra fiyatViagra 100 mg fiyatViagra 30 lu fiyatViagra 4 lü tablet fiyatıVega 100 mgVega 100 mg fiyatVega 100 mg eczaneKamagra jelKamagra Jel fiyatKamagra jel eczaneSertleştirici haplarGeciktirici ürünlercialiscinsel sağlık ürünleribayan azdırıcı fiyatkadın azdırıcı damlasertleştirici ilaçlarcialis fiyatviagra fiyatpenis büyütücükamagra jelgeciktirici spreycialis 20 mgcialis 100 mgviagra 30 luen iyi penis sertleştirici ilaçsertleştirici haplarelazığ escort bayanhasta yataklarıkent switch fiyatmarlboro shuffleparliament aqua bluemarlboro double fusionmarlboro shufflekent switchdjarum blackdjarum blackAnadolu yakası escortAtaşehir escortBostancı escortErenköy Escortavrupa yakası escortAtaköy EscortAvcılar EscortBahçeşehir Escortözel escortlaranal escortçıtır escortelit escortAnadolu Yakası escortAtaşehir escortbağdat caddesi escortBostancı escortGöztepe Escortİstanbul EscortKadıköy EscortKartal EscortKurtköy EscortMaltepe EscortPendik EscortŞerifali EscortTuzla EscortÜmraniye escortÜsküdar EscortAnadolu Yakası EscortAtaşehir escortBostancı EscortGöztepe EscortAvrupa Yakası EscortAksaray escortAtaköy EscortAvcılar Escortİstanbul EscortAtaşehir Elit EscortAtaşehir Esmer EscortAtaşehir Genç EscortAtaşehir Olgun EscortAtaşehir Sarışın EscortAtaşehir Şişman EscortAtaşehir Sınırsız EscortAtaşehir Ucuz EscortAtaşehir Yabancı EscortAteşehir Escort BayanBağdat Caddesi EscortBağdat Caddesi Olgun EscortBağdat Caddesi Sarışın EscortBağdat Caddesi Şişman EscortBağdat Caddesi Ucuz EscortBağdat Caddesi Yabancı EscortBostancı Elit EscortBostancı Çıtır EscortBostancı EscortBostancı Esmer EscortBostancı Olgun EscortBostancı Sarışın EscortBostancı Yabancı EscortGöztepe EscortGöztepe Genç EscortGöztepe Olgun EscortGöztepe Şişman EscortGöztepe Sınırsız EscortGöztepe Ucuz EscortKadıköy Anal EscortKadıköy Elit EscortKadıköy EscortKadıköy Eskort BayanlarKadıköy Genç EscortKadıköy Yabancı EscortKartal Çıtır EscortKartal EscortKartal Eskort BayanlarKartal Esmer EscortKartal Sarışın EscortKartal Sınırsız EscortKartal Ucuz EscortKaynarca EscortKaynarca Genç EscortKaynarca Olgun EscortKaynarca Şişman EscortKurtköy EscortKurtköy Escort BayanKurtköy Ucuz EscortKurtköy Yabancı Escort BayanMaltepe Anal EscortMaltepe EscortMaltepe Genç EscortMaltepe Olgun EscortMaltepe Şişman EscortPendik EskortPendik Eskort BayanlarPendik Sarışın EscortPendik Şişman EscortPendik Sınırsız EscortPendik Ucuz EscortTuzla Anal EscortTuzla Elit EscortTuzla EscortTuzla Yabancı EscortÜmraniye EscortÜmraniye Masöz EscortÜmraniye Olgun EscortÜmraniye Ucuz Escortepoksi zeminepoksi zemin kaplamaepoksi yol çizgisişişli escortAcıbadem Escortİçerenköy EscortKozyatağı EscortKüçükyalı EscortKadıköy EscortKartal EscortMaltepe EscortPendik EscortKurtköy EscortŞerifali EscortAnadolu Yakası EscortKadıköy EscortAtaşehir EscortBostancı EscortAtaşehir EscortKadıköy EscortKurtköy EscortAnadolu Yakası EscortAnadolu Yakası EscortAtaşehir EscortBostancı EscortKadıköy EscortAnadolu Yakası EscortKadıköy EscortAtaşehir EscortBostancı EscortMaltepe EscortGöztepe EscortPendik EscortErenköy EscortGöztepe EscortSuadiye EscortGöztepe EscortMaltepe EscortŞerifali EscortKartal EscortKurtköy EscortPendik EscortKurtköy EscortPendik EscortAnadolu Yakası EscortKartal EscortMaltepe EscortAnadolu Yakası EscortKartal Escort BayanKurtköy Escort BayanMaltepe Escort BayanPendik Escort BayanAnadolu Yakası EscortKartal EscortKurtköy EscortMaltepe EscortPendik EscortTuzla EscortKurtköy EscortPendik EscortTuzla EscortAnadolu Yakası EscortMaltepe EscortKartal EscortBostancı EscortÜmraniye EscortAnadolu Yakası EscortKadıköy EscortAtaşehir EscortTuzla EscortGebze EscortAydınlı EscortMutlukent EscortPendik EscortAnadolu Yakası EscortKurtköy EscortÜmraniye EscortBostancı EscortKartal Escort BayanPendik Escort BayanKurtköy Escort BayanMaltepe EscortAnadolu Yakası EscortBostancı EscortKartal EscortMaltepe EscortÜmraniye Escortbağdat caddesi escortgöztepe escortistanbul escortkartal escortkurtköy escortmaltepe escortpendik escorttuzla escortüsküdar escortataköy escortavcılar escort bayanavrupa yakası escortbahçeşehir escortbakırköy escortbeşiktaş escortbeylikdüzü escorterenköy escortetiler escortgöztepe escortikitelli escortkartal escortkurtköy escortmaltepe escortmecidiyeköy escortpendik escortşirinevler escortşişli escortsoğanlık escortataşehir escortkaynarca escortümraniye escortgebze escorttuzla escortavrupa yakası escortavrupa yakası escortavrupa yakası escortavrupa yakası escortavrupa yakası escortavrupa yakası escortavrupa yakası escortavrupa yakası escortavrupa yakası escortatalar escortcevizli escortescort bayanmaltepe escortbeylikdüzü escortavcılar escortesenyurt escortbahçeşehir escortşirinevler escortataköy escortbeylikduzuescortev.comescort beylikdüzüWhatsapp aerobeylikdüzü eskortbahariye escortmoda escortsex hikayeleriadana escortadıyaman escortafyon escortağrı escortaksaray escortamasya escortankara escortantalya escortantep escortardahan escortartvin escortaydın escortbalıkesir escortbartın escortbatman escortbayburt 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escortvega 100 mg hapseofuck googledolandırıcı hesap satışıviagrabacklink almetin2 pvppvp metin2metin2emek serveradana escortadana escortanadolu yakasi escortpendik escortistanbul escort